People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest. If applying on the scalp, wear a plastic shower cap. Use this medication on the skin only. During maintenance treatment, less itching and skin irritation were seen. Aluminum chloride (15 – 55% with or without 2 – 6% salicylic acid in a gel)IontophoresisAluminum chloride + Iontophoresis. This is not a complete list of possible side effects. What conditions does Aluminum Chloride Solution, Non- treat? [145], Following a recommended regimen may enhance efficacy and reduce the incidence of adverse effects. Stress Sweat Can Smell Worse than "Regular" Sweat, Here's Why & How to Deal It's... Hyperhidrosis and Beyond: Companies that Care in Surprising Ways. [23] Changing the vehicle could also enhance efficacy or reduce irritation. Do not use on broken skin, or skin that has recently been shaved. Aluminium Chloride (AlCl3) Uses. International Hyperhidrosis Society has received the GuideStar Exchange Seal a leading symbol of transparency and accountability provided by GuideStar, the premier source of nonprofit information. Let this medication dry completely before putting clothing over the treated area. Palmar hyperhidrosis is less responsive to aluminum chloride therapy,[148] and successful treatment may require concentrations up to 30%. Call your doctor for medical advice about side effects. [148] Aluminum chloride should remain on the skin for 6 to 8 hours to be effective. Otherwise, call a poison control center right away. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Some products that may interact with this drug include: deodorants, other antiperspirants, disulfiram, metronidazole, tinidazole. In a more recent study, 4% salicylic acid in a hydroalcoholic gel base was used as the vehicle for aluminum chloride hexahydrate in 238 patients with hyperhidrosis involving the axillae, feet, hands, and groin. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. If it is near the time of the next dose, skip the missed dose. Normal sweat gland function returns with epidermal renewal, however, necessitating retreatment once or twice a week. [58] Damage to fabrics also occurs, so expensive nightwear should be avoided. Aluminium Chloride is often regarded as a versatile chemical compound and therefore finds application in many areas, especially in chemical reactions and synthesis. © 2003-2020 International Hyperhidrosis Society. Before using this medication, tell your doctor or pharmacist your medical history. In the morning, wash the area with soap (or shampoo if treating the scalp) and water, and then towel dry. Your doctor may occasionally change your dose. If applying on the hands or feet, wrap the area with plastic wrap and cover with a mitten or sock. All rights reserved. [59] A mechanism underlying this obstruction has been proposed: the metal ions precipitate with mucopolysaccharides, damaging epithelial cells along the lumen of the duct and forming a plug that blocks sweat output. If applying on the underarms, wear a shirt. Although many recommend absolute alcohol as the best vehicle for minimizing irritation, a large series of patients followed for as long as a decade has shown that an aqueous vehicle thickened with methylcellulose to create a gel was the most effective formulation. Before using aluminum chloride, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Things to remember when you fill your prescription. If irritation persists beyond that point, a dermatology consult should be obtained. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. This product may contain inactive ingredients, which can cause allergic reactions or other problems. A very serious allergic reaction to this drug is rare. © 2005 - 2019 WebMD LLC. has been awarded as a Top-Rated NonProfit for, Social Embarrassment and Psychological Effects, Occupational Tasks and Activities of Daily Living, Starch Iodine + OnabotulinumtoxinA Injection Protocol for Axillary Treatment, About the International Hyperhidrosis Society. AlCl 3 is used mainly as a catalyst for different chemical reactions. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised June 2018. Do not get the medication in your eyes or apply it to broken, irritated, or recently shaved skin. Aluminum salt solutions are the most common antiperspirants in use today. The International Hyperhidrosis Society acknowledges the generosity of individual donors and Dermira Inc. (a wholly-owned subsidiary of Eli Lilly) whose support has helped make our 2020 Hyperhidrosis Awareness Month initiatives possible. [17,119,146] The most common adverse effects of aluminum chloride treatment are itching and stinging immediately after application and ongoing skin irritation. If you do get the medication on those areas, flush with plenty of water. If you miss a dose, use it as soon as you remember. Other approaches to aluminum chloride therapy include the addition of occlusion, with plastic wrap in the axillae and on the feet and vinyl gloves on the hands. [148] Irritated skin can be treated with topical HC cream for up to two weeks if irritation persists. During pregnancy, this medication should be used only when clearly needed.

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